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Written by: Maria Zavarce

Contributor: Lukas Wilgosh 

DJI M400 vs DJI M350 RTK

June 11th, 2025

3 minutes read

The moment we've been waiting for is here. DJI doesn’t just listen to its customers - they deliver. And now, they’ve raised the bar once again. The future of enterprise drones has arrived with the release of the DJI M400.

 

DJI’s Matrice 300 Series redefined the enterprise drone market, and the M350 RTK built on that legacy with smarter workflows and better stability. But the new M400 isn’t just an upgrade, it’s a transformation.

 

This article provides a detailed comparison between the DJI M400 and DJI M350 RTK, highlighting the most significant advancements in design, performance, payload, and technology.

Evolution from M350 RTK to M400

The M400 is built for larger-scale operations. It features a longer 1070 mm wheelbase and supports a maximum takeoff weight of 15.8 kg, nearly double that of the M350 (9.2 kg). While the M350 uses the TB65 battery system, the M400 introduces TB100 batteries, offering nearly four times the capacity. This enables flight times up to 59 minutes and greater payload flexibility.

 

The M400 also supports tethered flight natively and includes four E-Port V2 interfaces for payload mounting, compared to two on the M350. For teams that rely on modular payload setups or require persistent flight capability, this structural update is a significant advantage.

Key Specification Comparison

This table highlights the core differences between the DJI M400 and DJI M350 RTK enterprise drones, focusing on payload capacity, flight performance, transmission systems, intelligent features, and compatibility.
Feature DJI M400 DJI M350 RTK
Weight (with batteries and propellers) 9,740±40g 6,470g
Max Takeoff Weight 15.8kg 9.2kg
Max Payload 6kg 2.7kg
Payload Capacity 7 3
Flight Time (with H30T) 59 mins 42 mins
Max Horizontal Speed 25m/s 23m/s
Max Ascent/Descent Speed 10m/s (ascent), 8m/s (descent) 6m/s (ascent), 5m/s (descent)
Transmission System DJI O4 Enterprise Enhanced (20km CE, 40km FCC) DJI O3 Enterprise (8km CE, 20km FCC)
Ports USB-C, 4x E-Port V2, 2x Cellular Dongle 2x E-Port V2, 1x Cellular Dongle
Sensing System Full-colour fisheye, LiDAR (rotating and upper), mmWave radar 6-direction binocular and infrared vision
Obstacle Avoidance 24/7 (power-line-level) Standard directional vision + IR
Intelligent Features AI detection, AR projection, terrain follow, ship auto-landing, Smart 3D Capture Basic intelligent flight modes
IP Rating IP55 IP55
Operating Temperature -20°C to 50°C -20°C to 50°C
Wind Resistance 12m/s 12m/s
Battery TB100 (20,254 mAh, 977 Wh, Li-ion 13S) TB65 (5,880 mAh, 263.2 Wh, Li-ion 12S)
Battery Features Tethered support, 45-min fast charge (220V) No tethered support, 60-min charge (220V)
Spotlight (S1) Capabilities Auto alignment, remote control, 40 lux full beam Manual control, 35 lux full beam
Payload Compatibility Supports H30 Series, P1, L2, V1, S1 (no legacy H20 or L1) Supports same DJI payloads as M300, including legacy models

Payloads: More Room, More Possibilities

Payload flexibility is a major strength of the M400. It can carry up to 6 kg and accommodate up to seven payloads simultaneously across multiple mounting points. It’s designed to support DJI’s latest smart payloads, including the Zenmuse L2, P1, H30T, and S1.

 

While this makes the M400 more capable for high-precision tasks like photogrammetry, LiDAR mapping, and multi-sensor inspections, it’s worth noting that legacy payloads (such as the L1 or H20 series) are not compatible. The M350 continues to support these older payloads.

Flight Performance & Endurance

The M400 achieves a top horizontal speed of 25 m/s and a maximum range of 20 km in CE mode, significantly beyond the M350’s 8 km range. Its improved propulsion system supports more efficient ascents and descents, better wind resistance, and longer hover times.

 

These improvements are especially valuable in large-area missions or in applications where consistent flight endurance is key, such as corridor mapping, search and rescue, or long-range asset inspection.

Obstacle Avoidance & Sensing Systems

Safety and situational awareness have taken a substantial leap in the M400. It incorporates a multi-layered obstacle sensing system that includes rotating LiDAR, 3D infrared sensors, fisheye cameras, and millimeter-wave radar. This enables all-weather, low-visibility obstacle detection and terrain following, capabilities the M350’s standard 6-directional binocular vision system cannot match.

 

The enhanced sensors enable features like real-time terrain modelling, landing on dynamic surfaces such as moving vessels and safer autonomous navigation through complex environments.
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Autonomy, Control & Connectivity

The M400 is built with automation in mind. It integrates DJI’s O4 Enterprise transmission system, which provides dual-band (including sub-2GHz) connectivity, extended range, and improved reliability in complex RF environments. Autonomous capabilities include AI object recognition, real-time terrain following, and multi-drone coordination. 

 

While the M350 still offers reliable RTK performance and solid remote control, the M400’s AI-driven features provide meaningful advantages in high-demand sectors like energy, public safety, and infrastructure inspection.

Finally, the DJI M400 represents a clear leap forward in enterprise drone technology, pushing the boundaries of what’s possible in aerial operations. With increased payload capacity, extended flight time, enhanced obstacle sensing, and AI-driven autonomy, it’s designed for advanced missions that demand versatility, precision and safety.

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About the Author

Maria Zavarce, Marketing Coordinator at Measur, brings over two years of specialized experience in the drones and robotics industry. Combining her knowledge of emerging technologies with 8+ years of inbound marketing and SEO, she provides actionable insights into the transformative power of advanced solutions.
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